1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
  3. ATP Synthase

ATP Synthase (ATP合酶)

ATP 酶是一类催化 ATP 分解为 ADP 和游离磷酸根离子的酶。这种脱磷酸化反应会释放能量,酶(在大多数情况下)会利用这些能量来驱动其他原本不会发生的化学反应。一些此类酶是整合膜蛋白,它们会将溶质移过膜,通常是逆着其浓度梯度。这些酶被称为跨膜 ATP 酶。跨膜 ATP 酶会输入细胞代谢所需的许多代谢物,并输出可能阻碍细胞过程的毒素、废物和溶质。例如钠钾交换器(或 Na+/K+ ATP 酶)和氢钾 ATP 酶(H+/K+ ATP 酶或胃质子泵),它们会使胃内容物酸化。

ATPases are a class of enzymes that catalyze the decompositionof ATP into ADP and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. Some such enzymes are integral membrane proteins and move solutes across the membrane, typically against their concentration gradient. These are called transmembrane ATPases. Transmembrane ATPases import many of the metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes. Such as the sodium-potassium exchanger (or Na+/K+ ATPase) and the hydrogen potassium ATPase (H+/K+ ATPase or gastric proton pump) that acidifies the contents of the stomach.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-157045
    ATP Synthesis-IN-1 Inhibitor
    ATP Synthesis-IN-1 (Compound 4) 是喹啉衍生物,是 PA ATP 合成活性的有效抑制剂。 ATP Synthesis-IN-1 具有 PA ATP 合成抑制作用,IC50 值为 11.1μg/mL。ATP Synthesis-IN-1 还具有抗菌活性。 ATP Synthesis-IN-1可用于耐药PA感染的研究。
    ATP Synthesis-IN-1
  • HY-W779800
    D-α-Hydroxyglutaric acid-13C5 disodium Inhibitor
    D-α-Hydroxyglutaric acid-13C5 disodium 是 13C 标记的 D-α-Hydroxyglutaric acid (HY-113038)。稳定或放射性同位素标记的化合物可用于代谢分析,使得单个原子的动向能够被精准追踪和量化。
    D-α-Hydroxyglutaric acid-<sup>13</sup>C<sub>5</sub> disodium
  • HY-155754
    3′-Acetate-ATP Inhibitor
    3’-Acetate-ATP 是 ATP 类似物,是 ATP 乙酰化产物,在 259 nm 处具有最大紫外线吸收 (中性 pH 值的水中)。3’-Acetate-ATP 对核酸聚合发挥阻断作用。
    3′-Acetate-ATP
目录号 产品名 / 同用名 应用 反应物种